Will Ferrell, Best Night of Your Life 2 (Cancer for College)

Will Ferrell Announces “Best Night Of Your Life 2” Charity Show Set For October 21st in Los Angeles

Today, Will Ferrell has announced exclusively from Rolling Stone the second installment of his ‘Best Night of Your Life’, an out of this world night of music and comedy to benefit Cancer for College on Saturday, October 21, 2023 at the Greek Theatre in Los Angeles.

Who's joining Will Ferrell at this year's "Best Night of Your Life"?

The event will be hosted by Ferrell, who has recruited a star-studded lineup including comedians Jon Stewart, Hasan Minhaj, Jo Koy, Patti Harrison, Roy Wood Jr., Rory Scovel, plus a special appearance by SmartLess with Jason Bateman, Sean Hayes and Will Arnett. Mike McCready (Pearl Jam) has assembled an all-star musical lineup featuring Stefan Lessard (Dave Matthews Band), Beck, St. Vincent, Cindy Blackman Santana, Dogstar featuring Bret Domrose, Robert Mailhouse & Keanu Reeves, along with Jack Black and Fred Armisen who will perform as the one-time supergroup ‘Mike McCready and The Casual Acquaintances’, with additional performances by DJ White Shadow and Princess featuring Maya Rudolph and more specials guests on the way.

The first installment happened in 2018 at the Greek Theatre and featured Jerry Seinfeld, Jimmy Kimmel, Conan O’Brien, Samantha Bee, Michelle Wolf, Jerrod Carmichael, and Kumail Nanjiani.

Will Ferrell
Will Ferrell's Best Night of Your Life 2

What Will Ferrell had to say about this year's "Best Night of Your Life."

"Immediately upon completing our last show in 2018, I set out on a search of the cosmos,” said Will Ferrell. “The mission was to find the most incredible lineup of talent this world has ever seen. I think we can comfortably say mission accomplished. For those of you saying, ‘but Will, we've seen you a lot over the last five years in successful films, on popular streaming platforms and wildly funny TV appearances’, I'm here to tell you that cloning is real. Shoutout to Bill Ferrell, you did a hell of a job in my absence. My clones and I are super proud to be supporting the charity, Cancer for College. I think we can all get on board with hating cancer and the terrible things that can come with it. For 30 years, this organization has been providing need-based college scholarships, educational experiences and medical debt relief to cancer survivors. All the proceeds from the show will benefit the cause.”

This won’t be the first time that Will Ferrell and McCready take the stage together. The do-gooders have performed as part of one-off supergroups at a number of Cancer for College benefits over the years, including ‘Chad Smith’s Super Mega Funktastic Jam Rock All Stars’ alongside Chris Martin, Duff McKagan, Stefan Lessard, Josh Klinghoffer and Brad Paisley (2018), ‘Are You There God? It’s Me, Margaret’ featuring Chad Smith, Brandi Carlile, Josh Klinghoffer and Stefan Lessard (2018), and ‘I Pissed My Pants’ with Chad Smith and Brandi Carlile (2014).

“I can't wait to rock out at Will Ferrell's Best Night of Your Life 2!” said Mike McCready, Pearl Jam. “The first one in 2018 was an incredible experience. I'm stoked and honored to be putting together an amazing All-Star band for this event! You don't want to miss it!”

How to get tickets for Will Ferrell's "Best Night of Your Life 2."

Tickets for Best Night of Your Life 2 will go on sale Aug. 11 at 10 a.m. PT. A presale will start Aug. 9 at 10 a.m. PT via the Greek Theatre.

RELATED: Love Rory Scovel? Check out his full special Live Without Fear for free on 800 Pound Gorilla & download the album here.

RELATED: Love Jo Koy? Grab the vinyl & digital audio album from his Netflix special Live From Seattle on 800 Pound Gorilla.

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